The Mechanism of Vitamin D-assisted Treatment of Glucose and Lipid Metabolism in Diabetic Adipocytes by Confocal Microscopy

  • Yu Qin
Keywords: Confocal Microscopy, Diabetes, Vitamin D, Fat Cell Glycolipid Metabolism

Abstract

Diabetes is an endocrine and metabolic disorder. The formation mechanism of diabetes is affected by complex
factors. The main pathological mechanism is that liver, muscle and adipose tissue reduce the use of glucose,
increase the output of glycogen, resulting in hyperglycemia. In the aspect of fat metabolism, due to the
deficiency of insulin, the intake of glucose in adipose tissue and the removal of triglyceride in plasma decreased,
the synthesis of fat decreased, the activity of lipoprotein lipase decreased, and the concentration of free fatty
acid and triglyceride in blood increased. In recent years, many studies have shown that vitamin D has a very
good auxiliary effect on the treatment of diabetes. Therefore, this paper mainly studies the metabolism of fat
cells through the confocal microscope observation tool, and analyzes the indicators of different doses of vitamin
D in diabetic patients from the micro level. In order to verify the feasibility of the experiment, we followed 140
volunteers with real cases. The effects of body weight, Lee's index, organ index, serum 25 (OH) D content,
calcium and phosphorus content, blood glucose, insulin, adiponectin and lipid were studied. Finally, through the
comparative analysis of the data, we found that the use of large doses of vitamin D in a certain range of diabetic
patients can improve the nutritional level of UD and insulin, and can improve the weight of diabetic patients,
islet and muscle morphology abnormalities. This paper has played a complementary role in the study of the
mechanism of biotin d-assisted glycolipid metabolism of diabetic adipocytes.

Published
2020-06-01