Confocal laser Microscopy Study on the Histological Changes of Cornea after Phacoemulsification Cataract Extraction

  • Jing Shi
Keywords: Laser Scanning Confocal Microscope, Phacoemulsification Research, Cataract Removal, Corneal Histological Changes


The laser confocal microscope has a high resolution and can effectively observe the living corneal tissue after
cataract extraction. The purpose of this article is to solve some problems in phacoemulsification cataract
extraction and to explore the specific effect of using laser confocal microscopy to observe the living histological
changes of the cornea after phacoemulsification cataract extraction, in order to treat 20 cataracts in our hospital.
The patient was the subject of the study. Phacoemulsification cataract extraction was performed on the patient.
Confocal laser microscopy was used to scan the corneal living tissue of the patient after surgery. The scanned
images of each layer of corneal living tissue were recorded, and the histological changes of the patient's cornea
were analyzed and studied. The results show that the laser confocal microscope can clearly show the specific
morphology of each layer of corneal living tissue, and the observation accuracy is improved by 25.7%. After
phacoemulsification surgery, 14.6% of corneal stromal nerve fiber tissue changes, the medium matrix and the
posterior stromal layer. The corneal cell reflectance increased by 18.5% compared to before surgery. At the same
time, the nucleus and cytoplasm of corneal endothelial cells were slightly swollen. It can be seen that
phacoemulsification cataract extraction will cause changes in corneal living tissue. Confocal laser microscopy
can effectively observe the morphology of the cornea after phacoemulsification cataract extraction.