The Effect of Electroacupuncture on the Pathology and Ultrastructure of Brain Tissue around Hematoma in Rats with Cerebral Hemorrhage

  • Sheng Lu
Keywords: Electroacupuncture, Intracerebral Hemorrhage Rats, Brain Histopathology around Hematoma, Ultrastructure

Abstract

To explore the effect of Electroacupuncture on the pathology and ultrastructure of brain tissue around hematoma
in rats with intracerebral hemorrhage, and analyze its target and mechanism. 60 rats were randomly divided into
two groups, 30 rats in each group. The control group was fed regularly every day, and the observation group was
stimulated by electroacupuncture. Two weeks later, the brain was harvested and the brain water content, MMP-9,
AQP4, VEGF protein expression levels were compared between the two groups. Compared with the control
group, the level of MMP-9, AQP4 and VEGF in the observation group decreased significantly (P < 0.05).
Electroacupuncture can significantly reduce the damage of nerve cells and ultrastructure, inflammatory cell
infiltration and brain edema in the acute stage of cerebral hemorrhage in rats. It suggests that electroacupuncture
has an antagonistic effect on brain tissue injury and brain edema. It can protect the brain, inhibit brain edema
and repair brain nerve function by inhibiting the expression of MMP-9, AQP4 and VEGF.

Published
2020-06-25