The Relationship between the Expression Level of Serum Complement C1q TNF Related Protein 3 and Premenopausal Female Coronary Heart Disease

  • Shijie Wang
Keywords: CTRP3, Premenopausal Female Coronary Heart Disease

Abstract

To explore the relationship between the expression level of serum complement C1q tumor necrosis  factor-related protein 3 (ctrp3) and premenopausal coronary heart disease (CHD) in women, and to formulate the intervention methods and analyze them. From December 2018 to December 2019, 120 female patients with coronary heart disease in our hospital were selected as the research objects. According to the menopause time, they were divided into observation group and control group, 60 cases each. The observation group was premenopausal coronary heart disease; the control group was Postmenopausal Coronary heart disease. The changes of inflammatory factors such as ctrp3, CRP, IL-10 and TNF - α in serum were detected. Compared with the control group, the expression level of ctrp3 in the observation group increased significantly, the difference was statistically significant (P < 0.05); compared with the control group, the expression level of CRP in the observation group decreased significantly, the difference was statistically significant (P < 0.05); compared with the control group, the expression water of IL-10 in the observation group increased significantly, the difference was statistically significant (P < 0.05); compared with the control group, the expression water of TNF - α in the observation group was statistically significant (P < 0.05) The difference was statistically significant (P < 0.05). The expression level of serum complement C1q tumor necrosis factor associated protein 3 (ctrp3) can effectively indicate the improvement of symptoms in premenopausal women with coronary heart disease, which is negatively correlated with the severity of coronary heart disease.

Published
2020-05-01