Analysis of Early Rebleeding Rate and Related Factors after Esophageal Varices in Patients with Liver Cirrhosis

  • Xiangquan Song
Keywords: Cirrhosis Research, Varicose Veins, Endoscopic Treatment, Early Rebleeding

Abstract

Esophageal varices are a common complication of liver cirrhosis, and esophageal varices bleeding is one of the
common causes of death in patients with advanced liver cirrhosis. With the advancement of diagnosis and
treatment technology, the mortality of patients with esophageal varices bleeding has decreased, but still as high
as 20%. Therefore, active prevention of esophageal varices bleeding and effective hemostasis are important
measures to improve the survival of patients with decompensated liver cirrhosis. The purpose of this article is to
explore the early rebleeding rate and its related factors after endoscopic treatment in patients with moderate to
severe esophageal varices in liver cirrhosis. By comparing relevant clinical data of early rebleeding and no
rebleeding patients after treatment, a Logistic regression model is used. Analysis of influencing factors of early
rebleeding after endoscopic treatment. The results showed that 22 of the 216 patients had early postoperative
rebleeding, with an early rebleeding rate of 10.2%. Multivariate analysis showed that prothrombin time, ligation
varicose points, and portal vein thrombosis were influential factors for early rebleeding after endoscopic
treatment in patients with moderate or severe esophageal varices (P <0.05). Patients with moderate or severe
esophageal varices with prothrombin time, high ligated varices, and portal vein thrombosis are more likely to
have early rebleeding after endoscopic treatment. At the same time, platelet count, varicose vein degree, red sign,
and Child-Pugh grade of liver function are independent risk factors for early rebleeding after endoscopic
treatment of esophageal and gastric varices in cirrhosis.

Published
2020-02-01